A pH meter is an electronic device used for measuring the pH (acidity or alkalinity) of a liquid (though special probes are sometimes used to measure the pH of semi-solid substances). A typical pH meter consists of a special measuring probe (a glass electrode) connected to an electronic meter that measures and displays the pH … Read more
Formulation of the coating solution: Adequate preparation of the coating solution is essential for achieving an effective coating within a reasonable timeframe. This solution is prepared in S S vessels equipped with a stirrer. Various techniques are beneficial in facilitating the prompt formulation of coating solutions: Dispersion in hot water: The coating materials remain insoluble … Read more
Forming Temperature: The quality of the pockets that form is determined by the forming temperature. It depends on the type of packaging material and the unit’s dimensions. Sealing Temperature: It establishes the outcomes of the leak test. Pressure and plate knurling are both involved. Speed of machine: It varies from machine to machine and is determined by: i) Product Features: Size, Hardness, Shape, and Dispersible Tablets. b) According to the kind of packing materials that are utilized. Pressure: It influences product quality and can be used for cold forming and blister sealing. Leak Test: Leak test is performed to assess the possibilities of leaks in the blister and all blisters after checking should not contain water inside any pocket. Common Issues in Blister packing:
What exactly is a Blister Pack? Blister packaging is a process that entails shaping a heat-softened plastic film into deep-drawn pocket molds to create a tray (thermoforming), followed by filling it with a solid dosage form product and sealing it with either a push-through or peelable cover. Adequate heat and pressure must be applied to … Read more
The following factors are used to choose an auditor for vendor qualification: 1. Experience and Qualifications: 2. Technical Proficiency: 3. Auditing Proficiency: 4. Self-reliance and impartiality: 5. References and Reputation: 6. Adherence to Regulatory Mandates: 7. Audit Methodology and Approach: Organizations can choose a skilled auditor to assess vendors and guarantee adherence to industry standards and legal obligations by taking these factors into account.
“Good Laboratory Practice (GLP) is concerned with the organizational process and the conditions under which laboratory studies are planned, performed, monitored, recorded, and reported.” GLP prescribes a laboratory to work according to a system of procedures and protocols. This implies the organization of the activities and the conditions under which these take place are controlled, … Read more
Water is commodiously used as a raw material, ingredient, and solvent in the processing, formulation, and manufacture of pharmaceutical products, active pharmaceutical ingredients (APIs) and intermediates, and analytical reagents. Types of Water: Raw Water: Raw water is a natural water available in the environment, such as rainwater, ground water, and water from bodies like lakes … Read more
What is Blister Pack? Blister packaging involves forming a heat softened plastic film into a deep drawn pocket moulds to form a tray (thermoforming), filling with a solid dosage form product and sealing with a push through or peel able covering. Appropriate heat and pressure must be applied to ensure that permanent sealing will be … Read more
Packaging is defined as the collection of different components which surround the pharmaceutical product from the time of production until its use. Importance of packaging: It is important to produce a pharmaceutical product with high quality standards and even it is more important to protect that product form the degradation, external contamination and other physical/chemical … Read more
Risk assessment consists of the identification of hazards and the analysis and evaluation of risks associated with exposure to those hazards as defined below. Quality risk assessments begin with a well-defined problem description or risk question. When the risk in question is well defined, an appropriate risk management tool and the types of information needed … Read more
