GRANULATION PROCESS IN PHARMACEUTICAL MANUFACTURING:

Granulation is required to improve the flow of powder mixtures and mechanical properties of Tablet. Granulation is the act or process in which primary powder particles are made to adhere to form larger, multiparticle entities called granules. It is the process of collecting particles together by creating bonds between them. Bonds are formed by compression … Read more

Sifting Process in Pharmaceutical Manufacturing:

Sifting is a screening process to exclude foreign matter / particles (if any) and particles beyond the required size. Sifting is carried out by allowing particles to pass through specified mesh under the influence of vibration and gyration. The mesh (sieve) size is specified as the number of pores on 1 inch. Example 100 mesh … Read more

Unit Operations during manufacture of Tablets:

Unit Operations: The manufacture of Tablets is a complex multi-stage process under which the starting materials change their physical characteristics a number of times before the final dosage form is produced. Numerous unit operations are involved in making Tablets including sifting, mixing, granulation, drying, sizing, blending, lubrication, compression and coating. DISPENSING OF RAW MATERIALS (API … Read more

Handling of Product quality complaints

Handling of Product quality complaints in pharmaceutical Industry: Product quality complaints are also known as Market complaints, customer complaints, Technical complaints, quality complaints, etc. What is complaint: A written or verbal communication received from Consumer, end-user, Client, Caregiver, Pharmacy, Regulatory authority, government agency, Qualified Person, Responsible Pharmacist, Retailer, Distributor, field staff, contract giver,  beneficiary, purchaser … Read more