COMPRESSION PROCESS IN PHARMACEUTICAL MANUFACTURING

TABLET COMPRESSION: Reducing the bulk volume of a powder by applying mechanical force so as to form a defined shape of desired weight and strength is called ‘Compression’. Tablet compression is the process of squeezing powders together and driving out the air between the particles, resulting in a compressed Tablet. WHY COMPRESSION? TABLET PRESS OR … Read more

BLENDING PROCESS IN PHARMACEUTICAL MANUFACTURING:

BLENDING PROCESS: Blending of solid particles refers to mixing of solids with the aim of attaining a uniform composition throughout the mix. In powder blending two or more dissimilar particulate solids are blended to give a random mix. Objective of blending is to form a homogeneous final product from two or more dissimilar raw materials. … Read more

MILLING PROCESS IN PHARMACEUTICAL MANUFACTURING:

MILLING PROCESS: Milling process is also called as ‘screening’ and ‘sizing’ process. Milling is employed between RMG and Blending to crush the larger particles from granulation into uniform small particles which meets the process requirement. Milling isperformed to remove lumps, improve flow, reduce segregation and to control the particle size. Milling is performed by using … Read more

GRANULATION PROCESS IN PHARMACEUTICAL MANUFACTURING:

Granulation is required to improve the flow of powder mixtures and mechanical properties of Tablet. Granulation is the act or process in which primary powder particles are made to adhere to form larger, multiparticle entities called granules. It is the process of collecting particles together by creating bonds between them. Bonds are formed by compression … Read more

Sifting Process in Pharmaceutical Manufacturing:

Sifting is a screening process to exclude foreign matter / particles (if any) and particles beyond the required size. Sifting is carried out by allowing particles to pass through specified mesh under the influence of vibration and gyration. The mesh (sieve) size is specified as the number of pores on 1 inch. Example 100 mesh … Read more