Equipment must be located, designed, constructed, adapted, and maintained to suit the operations to be carried out. The layout and design of equipment must aim to minimize the risk of errors and permit effective cleaning and maintenance in order to avoid cross-contamination, build-up of dust or dirt, and, in general, any adverse effect on the … Read more
Formulation of Capsules includes active ingredient and excipients (Fillers, Disintegrant and Glidant / Lubricant). Particle size distribution (PSD) and bulk density (BD/TD) of API/Excipients is important parameter in the selection of capsule size. Determination of appropriate capsule size for formulation: Blend with BD 0.4 g/cc and fill weight 200 mg to filled D= M/V 0.4 … Read more
CAPSULES: Capsules are solid dosage forms in which medicinal agents are enclosed within hard or soft soluble shell of gelatin. The capsules are regarded as container drug delivery system that provides a tasteless/odorless dosage form without need for secondary coating step. Advantages of Capsules: Disadvantages of Capsules: TYPES OF CAPSULES: Capsules can be broadly classified … Read more
